Pyridine, 2-methoxy-4-methyl-

Name	2-Methoxy-4-methylpyridine
Synonyms	2-Methoxy-p-picoline 2-METHOXY-4-PICOLINE 2-Methoxy-4-methylpyridine 2-METHOXY-4-METHYLPYRIDINE 2-METHOXY-4-METHYLPYRIDINEV Pyridine, 2-methoxy-4-methyl- Pyridine, 2-methoxy-4-methyl- (9CI) 2-METHOXY-4-PICOLINE (2-METHOXY-4-METHYLPYRIDINE)
CAS	100848-70-2
InChI	InChI=1/C7H9NO/c1-6-3-4-8-7(5-6)9-2/h3-5H,1-2H3

Molecular Formula	C7H9NO
Molar Mass	123.15
Density	1.001±0.06 g/cm3(Predicted)
Melting Point	136 °C
Boling Point	152-153 °C (lit.)
Flash Point	53°C
Vapor Presure	1.3mmHg at 25°C
Appearance	clear liquid
Color	Colorless to Almost colorless
pKa	4.07±0.10(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.4990-1.5030

Hazard Symbols	Xi - Irritant
Risk Codes	R10 - Flammable R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
UN IDs	UN 1993 3/PG 3
WGK Germany	3
HS Code	29339900
Hazard Note	Irritant
Hazard Class	3
Packing Group	Ⅲ

Introduction	2-methoxy-4-methylpyridine is an organic intermediate, it can be prepared by nucleophilic substitution of 2-chloro-4-methylpyridine with sodium methoxide.
Use	2-methoxy-4-methylpyridine is a heterocyclic organic compound that can be used as an organic intermediate.
preparation	2-chloro-4-methylpyridine (20g,0.156mol) and NaOCH3(9.3g,0.172mol) the mixture in DMSO (100 ml) was stirred at °c for 4 hours. The solution was added to H2O and then extracted with ethyl acetate (50ml x 2). The organic layer was washed with H2O (46% ml), brine (ml), and dried and concentrated to give 2-methoxy-4-methylpyridine (9g,). LC-MS:124[M + H]+,tR = 1.21 min.

Last Update：2024-04-09 02:00:04

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CAS: 100848-70-2
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